This article outlines the Italian financial transaction tax implications of some of the new MiFID II and MiFIR rules for the EU financial markets. In particular, it focuses on the main changes to the market structure framework (distinction between bilateral and multilateral trading, MiFID II trading venues, trading obligation for shares and MiFID II trading capacities) and analyses the availability of the reduced Italian financial transaction tax rate/charges for trades executed on regulated markets and multilateral trading facilities.