Transfer pricing continues to be the most important international tax issue that many multinational enterprises face, according to the 2007-2008 Transfer Pricing Global Survey by Ernst & Young. This article provides insights regarding what has changed since this journal began featuring coverage of the Survey in 2000, the importance of regulatory developments, the changed focus due to risk management and specific trends that are prevalent in today's environment. It also provides key insights into best practices that have been developed by MNEs in dealing with transfer pricing on a global level.